Traumatic brain injury during development reduces minimal clonic seizure thresholds at maturity
نویسندگان
چکیده
منابع مشابه
Traumatic brain injury during development reduces minimal clonic seizure thresholds at maturity.
Post-traumatic seizures affect 12-35% of children after traumatic brain injury (TBI) and are associated with worse cognitive and functional outcome, even after adjustment for severity of injury. Unfortunately, experimental models of pediatric post-traumatic epilepsy are lacking, and pathogenesis remains poorly understood. We have applied a standard model of TBI in immature rats to determine the...
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traumatic brain injury (tbi) is an important clinical problem in the worldwide and especially due to breaking driving rules in iran, but undesirable consequences of trauma can persist for the rest of patient’s life. we investigated the effect of a novel weight drop model of tbi on incidence of seizure 2 weeks after tbi. in this regard, 21 male wistar rat weighted 250-300 gr randomly were divide...
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ژورنال
عنوان ژورنال: Epilepsy Research
سال: 2008
ISSN: 0920-1211
DOI: 10.1016/j.eplepsyres.2008.04.001